Details

NF-kB/Rel Transcription Factor Family


NF-kB/Rel Transcription Factor Family


Molecular Biology Intelligence Unit

von: Hsiou-Chi Liou

149,79 €

Verlag: Springer
Format: PDF
Veröffentl.: 26.02.2007
ISBN/EAN: 9780387335735
Sprache: englisch
Anzahl Seiten: 185

Dieses eBook enthält ein Wasserzeichen.

Beschreibungen

<P>Since its first discovery in the early 90’s, the NF-kB/Rel transcription factor family has drawn the attention of experimental biologists, medical profession, and biotech/pharmaceutical industries for its broad and diverse roles in all aspects of human biology and disease. NF-kB/Rel Transcription Factor Family intends to provide an up-to-date guide to the ever-expanding knowledge in the field of NF-kB/Rel transcription factor family. </P>
Structural Analysis of NF-?B and I?B Proteins.- NF-?B Signal Transduction by IKK Complexes.- Receptors and Adaptors for NF-?B Signaling.- Cellular Dynamics of NF-?B Associated Proteins.- NF-?B in Lymphopoiesis.- NF-?B and Immune Cell Effector Functions.- Roles of NF-?B in Autoimmunity.- The Central Role of NF-?B in the Regulation of Immunity to Infection.- Molecular Basis of Oncogenesis by NF-?B.- NF-?B in Human Cancers.- NF-?B in Neurons.- Inhibitors of NF-?B Activity.
Written by experts of the field, NF-kB/Rel Transcription Factor Family covers topics from structural basis and molecular mechanism of NF-kB signal transduction, transcriptional regulation, and target gene expression to the roles of NF-kB in biological and pathological processes. Includes supplementary material: sn.pub/extras

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